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CosDNA > 化妝品、保養品成分查詢分析 > Octinoxate
Octinoxate
(Octylmethoxy Cinnamate, Octyl Methoxycinnamate, Ethylhexyl methoxycinnamate, 2-Ethylhexyl 4-methoxycinnamate, 2-Ethylhexyl-p-methoxycinnamate, Parsol MCX, Escalol 557)
桂皮酸鹽, 4-甲氧基肉桂酸-2-乙基己基酯, 甲氧基肉桂酸辛酯, 2-羥基-4-甲氧基二苯甲酮, 甲氧基肉桂酸乙基己酯

分子量:290
Cas No:5466-77-3
致粉刺刺激性來源
00Sage Advice

紫外線吸收劑,可以阻隔 UVB 290-320,為防曬成份,目前全世界被廣為採用的化學防曬成份。衛生署限量10%。

防曬成份,油性化學性紫外線吸收劑,危險指數為 2/5(越高越不好)[1]。
[1] 張麗卿,『優質保養品選擇策略』,聯經出版社,2003/07/10。
註明出自 CosDNA,並提供連結 http://www.cosdna.com 方可引用本資料

修訂:2009-06-24
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skyline_612
  
2008-12-04 14:24
刺激性高嗎?
最少可加多少%?
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skyline_612
  
2008-12-04 14:24
刺激性高嗎?
最高可加多少%?
teco0726
  
2009-08-14 07:21 
最高只可到10% ,刺激性算低 ,

在防曬產品中很常見
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blueriver
  
2010-02-28 23:20
日文:
メトキシケイヒ酸エチルヘキシル、
メトキシケイヒ酸オクチル、
パラメトキシケイ皮酸2-エチルヘキシル,
參見:http://www.ba-m-bi.com/seibun/gaiyo/metokisi.htm
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alicelau
  
2010-06-06 19:54
对皮肤的刺激性小,但在动物试验中观察到其对雌激素有所影响,浓度限量10%。
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yixuan_126
  
2012-10-16 17:06
干扰正常内分泌。
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rs121
  
2013-06-06 13:05
请问它的危险体现在哪里
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yan1221
  
2014-01-15 16:01
Extensive research has shown that a number of UV filters frequently used in the formulation of commercial sunscreens, such as 4 MBC, octyl methoxycinnamate, oxybenzone (benzophenone-3), octyl-dimethyl-PABA and octinoxate, possess endocrine activity. Endocrine disruptors are chemicals that interfere with endogenous hormone action and/or production. These have been implicated in the development of a number of diseases in both males and females, including cancer of the mammary glands and reproductive organs, as well as the abnormal development of the male reproductive system. In one study, the application of three active ingredients commonly found in sunscreens (oxybenzone, 4-MBC and octinoxate) for one week led to a drop in testosterone and estradiol levels in men. More worrying is that these chemicals have been found in breast milk at concentrations known to have oestrogenic effects.
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sofiekk
  
2015-08-16 18:16
這個成分晚上塗了會堵塞毛孔嗎?
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dreamivan69
  
2016-05-25 19:20
這個成分是皮膚炎的過敏原之一,不適合敏感肌用
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okaypore
  
2016-06-12 16:22
同关心,为什么这个长期危险性评分为6这么高?【我自己就长期使用这款产品....
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ruru
  
2016-06-24 14:46
桂皮酸鹽(octinoxate)會導致男性體內睪固酮下降。
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ruru
  
2016-06-30 17:16
一個或多個人類病例研究表明可能有光敏性或過敏作用
一個或多個動物的研究表明在高劑量有發展的影響
一個或多個動物的研究表明在高劑量有生殖的影響
一個或多個動物的研究表明在高劑量有肝臟的影響
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mill0625
  
2016-09-23 14:10
不建議使用的物質
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helen114
  
2016-11-26 21:37
在安全浓度限量內使用安全?
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tomboy77
  
2016-12-22 14:25 
甲氧基肉桂酸辛酯 (Octinoxate)
作用是以吸收陽光中的中波紫外線(UVB),保護皮膚免於其傷害,是目前最常廣泛使用的 UVB 防曬乳。甲氧基肉桂酸辛酯對皮膚刺激性小,但卻會擾亂荷爾蒙、造成皮膚老化,並產生自由基破壞皮膚細胞。
http://news.everydayhealth.com.tw/2015/06/25/5773-%E8%81%B0%E6%98%8E%E6%8C%91%E9%81%B8%EF%BC%816%E7%A8%AE%E9%98%B2%E6%9B%AC%E4%B9%B3%E5%8D%B1%E9%9A%AA%E6%88%90%E5%88%86%E5%A4%A7%E5%89%96%E6%9E%90
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ju82831
  
2017-05-31 21:14
即便在低劑量的情況下,會刺激珊瑚的共生藻體內的病毒攻擊共生藻,間接使珊瑚白化甚至死亡,而共生藻死亡後的病毒被釋入海水後,導致周邊海水病毒濃度增加,提高了其他珊瑚體內共生藻的感染率。

資料來源:環境資訊中心TEIA
bigmomo
  
2018-07-17 13:14
Regarding safety, there are also some concerns around Octinoxate. In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects. Do not panic, the studies were not conducted under real life conditions on real human people, so it is probably over-cautious to avoid Octinoxate altogether. However, if you are pregnant or a small child (under 2 yrs. old), choose a physical (zinc oxide/titanium dioxide) or new-generation Tinosorb based sunscreen, just to be on the super-safe side. :)

Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent. There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US).
https://incidecoder.com/ingredients/ethylhexyl-methoxycinnamate
lilacKaZ
  
2019-04-16 18:44
https://www.medpartner.club/wp-content/uploads/2017/07/%E9%98%B2%E6%9B%AC%E7%B3%BB%E5%88%975_%E8%A1%A8%E6%A0%BC.png
lilacKaZ
  
2019-04-16 18:46
美的好朋友製作的表格
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