Data on the PEG ingredients indicated that when used on burn patients, PEGs may result in kidney effects.(燒傷患者使用時，聚乙二醇，可能會導致腎功能的影響。)
Therefore, the CIR Expert Panel also concluded that the Ceteareth ingredients should not be used on damaged skin. Ceteareth-15 (10% in formulation) was minimally irritating after a single dermal exposure.(不應使用對受損皮膚)