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Siped®PP-3 Palmitoyl Pentapeptide-3
Siped®PP-3 is a solution containing 120 ppm of lipopeptide Pal-Lys-Thr-Thr-Lys-Ser (pal-KTTKS). Pal-KTTKS has comparable efficacy to retinol without skin barrier damage.

INCI Glycerin - Water (Aqua) - Butylene Glycol - - Palmitoyl Pentapeptide-3

CAS 214047-00-4

Sequence Pal-Lys-Thr-Thr-Lys-Se

Properties and benefits

Pal-KTTKS has comparable efficacy to retinol. In clinical trials, topical 3 ppm pal-KTTKS has demonstrated efficacy in reducing fine facial lines/wrinkles.

• Stimulation of collagen I ,III, IV and fibroblasts synthesis;

• Reduces excess dermal glycosaminoglycans found in older skin;

• Increases epidermal thickness.

In contrast to retinol, pal-KTTKS did not induce irritation even at much higher levels


Products for wrinkle prevention and repair, eye contour care.

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